An olive oil-rich diet results in higher concentrations of LDL cholesterol and a higher number of LDL subfraction particles than rapeseed oil and sunflower oil diets.
Study Goal
The researchers aimed to compare the effects of rapeseed oil, olive oil, and sunflower oil on blood lipids, lipoproteins, and lipoprotein subclasses in healthy young men.
Results Summary
Rapeseed oil and sunflower oil showed more favorable effects on blood lipids, plasma apolipoproteins, and LDL subfractions compared to olive oil, with lower cholesterol, triacylglycerol, and LDL concentrations. HDL(2a) cholesterol was higher after rapeseed oil consumption compared to sunflower oil.
Population
18 young, healthy men
Effective Dosage
50 g of oil per 10 MJ incorporated into a constant diet
Duration
3-week intervention period
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
olive oil diet | increase | Plasma cholesterol, triacylglycerol, apolipoprotein B, and very low density lipoprotein (VLDL), intermediate density lipoprotein (IDL), and low density lipoprotein (LDL) cholesterol concentrations | Eighteen young, healthy men | 10;-20% | were 10;-20% higher | #1 |
olive oil diet | no change | The size of IDL, VLDL, and LDL subfractions | Eighteen young, healthy men | - | did not differ | #2 |
olive oil diet | increase | larger and medium-sized LDL subfractions | Eighteen young, healthy men | - | a significantly higher number (apolipoprotein B concentration) and lipid content | #3 |
olive oil diet | no change | Total HDL cholesterol concentration | Eighteen young, healthy men | - | did not differ significantly | #4 |
olive oil diet | increase | HDL(2a) cholesterol | Eighteen young, healthy men | - | was higher | #5 |
rapeseed oil diet | increase | HDL(2a) cholesterol | Eighteen young, healthy men | - | was higher | #6 |
rapeseed oil and sunflower oil | decrease | blood lipids and plasma apolipoproteins as well as on the number and lipid content of LDL subfractions | Eighteen young, healthy men | - | had more favorable effects | #7 |
We investigated the effect of olive oil, rapeseed oil, and sunflower oil on blood lipids and lipoproteins including number and lipid composition of lipoprotein subclasses. Eighteen young, healthy men participated in a double-blinded randomized cross-over study (3-week intervention period) with 50 g of oil per 10 MJ incorporated into a constant diet. Plasma cholesterol, triacylglycerol, apolipoprotein B, and very low density lipoprotein (VLDL), intermediate density lipoprotein (IDL), and low density lipoprotein (LDL) cholesterol concentrations were 10;-20% higher after consumption of the olive oil diet compared with the rapeseed oil and sunflower oil diets [analysis of variance (ANOVA), P < 0.05]. The size of IDL, VLDL, and LDL subfractions did not differ between the diets, whereas a significantly higher number (apolipoprotein B concentration) and lipid content of the larger and medium-sized LDL subfractions were observed after the olive oil diet compared with the rapeseed oil and sunflower oil diets (ANOVA, P < 0.05). Total HDL cholesterol concentration did not differ significantly, but HDL(2a) cholesterol was higher after olive oil and rapeseed oil compared with sunflower oil (ANOVA, P < 0.05).In conclusion, rapeseed oil and sunflower oil had more favorable effects on blood lipids and plasma apolipoproteins as well as on the number and lipid content of LDL subfractions compared with olive oil. Some of the differences may be attributed to differences in the squalene and phytosterol contents of the oils.