[The treatment of coronary heart disease by beta-adrenoblockers or tiazide diuretics preparation in combination with vegetarian diet].
Study Goal
The researchers aimed to compare the effects of a lacto-ovo vegetarian diet versus a standard antiatherogenic diet on cholesterol levels and atherogenic coefficient in patients with coronary heart disease.
Results Summary
The vegetarian diet led to significant reductions in total cholesterol (16%), LDL cholesterol (18%), and atherogenic coefficient (31%), while the standard diet showed minimal changes. Hypotiazide combined with the vegetarian diet also resulted in slight improvements in cholesterol levels.
Population
84 patients with coronary heart disease, divided into two equal groups.
Effective Dosage
Not specified for the diet; medications: athenolol (50 mg daily) and hypotiazide (25 mg daily).
Duration
24 days
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
athenolol (50 mg daily) + antiatherogenic lactoovovegetarian diet | decrease | level of total cholesterol | patients with coronary heart diseases | 16% | decreased | #1 |
athenolol (50 mg daily) + antiatherogenic lactoovovegetarian diet | decrease | low-density lipoproteins cholesterol | patients with coronary heart diseases | 18% | decreased | #2 |
athenolol (50 mg daily) + standard antiatherogenic diet 10c | no change | level of total cholesterol | patients with coronary heart diseases | no significant change | practically did'nt change | #3 |
athenolol (50 mg daily) + standard antiatherogenic diet 10c | no change | low-density lipoproteins cholesterol | patients with coronary heart diseases | no significant change | practically did'nt change | #4 |
antiatherogenic lactoovovegetarian diet | decrease | atherogenic coefficient (KA) | patients with coronary heart diseases | 31% | decreased | #5 |
standard antiatherogenic diet 10c | no change | atherogenic coefficient (KA) | patients with coronary heart diseases | no significant change | showed only a tendency for decreasing | #6 |
hypotiazide (25 mg daily) + antiatherogenic lactoovovegetarian diet | decrease | total cholesterol | patients with coronary heart diseases | slight | slight decrease | #7 |
hypotiazide (25 mg daily) + antiatherogenic lactoovovegetarian diet | decrease | KA levels | patients with coronary heart diseases | slight | slight decrease | #8 |
hypotiazide (25 mg daily) + antiatherogenic lactoovovegetarian diet | increase | HDL cholesterol | patients with coronary heart diseases | slight | slight increase | #9 |
Work make on 84 patients with coronare heart diseases were divided into two groups, equal quantity. The first groups were given athenolol (50 mg daily), the second--hypotiazide (25 mg daily). In every groupspart patients received an antiatherogenic lactoovovegetetarian diet, part--an standard antiatherogenic diet 10c. Time observation--24 daily. By the end of the treatment period with athenolol in backoground the vegetarian diet the level of total cholesterol decreased by 16%, low-density lipoproteins cholesterol decreased by 18%. In groups patients received an standard antiatherogenic diet these parameters practically did'nt change. In the vegetarian group the atherogenic coefficient (KA) decreased by 31%., while in the patients on standard antiatherogenic diet KA showed only a tendency for decreasing. By the end to the treatment period with hypotiazide the slight decrease in total cholesterol, KA levels and a slight increase in HDL cholesterol were observed only the vegetarian group.