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Dietary supplementation with chickpeas for at least 5 weeks results in small but significant reductions in serum total and low-density lipoprotein cholesterols in adult women and men.

Annals of nutrition & metabolism
May 5, 2006
J K Pittaway et al. (7 authors)
Comparative StudyJournal ArticleMulticenter StudyRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

To compare the effects of a chickpea-supplemented diet versus a wheat-supplemented diet on human serum lipids and lipoproteins.

Results Summary

The chickpea-supplemented diet significantly lowered serum total cholesterol (3.9%) and LDL cholesterol (4.6%) compared to the wheat-supplemented diet. Small but significant differences in macronutrient intake (protein, monounsaturated fat, and carbohydrates) were observed, with multivariate analyses suggesting the lipid differences were due to variations in polyunsaturated fatty acids and dietary fiber.

Population

Forty-seven free-living adults.

Effective Dosage

Not specified (dietary supplementation).

Duration

At least 5 weeks per dietary period.

Interactions

None mentioned.

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
chickpea-supplemented diet
decrease
serum total cholesterol levels
forty-seven free-living adults
3.9%
were significantly lower
#1
chickpea-supplemented diet
decrease
low-density lipoprotein cholesterol levels
forty-seven free-living adults
4.6%
were significantly lower
#2
chickpea-supplemented diet
decrease
protein intakes
forty-seven free-living adults
0.9% of energy
were slightly but significantly lower
#3
chickpea-supplemented diet
decrease
monounsaturated fat intakes
forty-seven free-living adults
3.3% of total fat
were slightly but significantly lower
#4
chickpea-supplemented diet
increase
carbohydrate intake
forty-seven free-living adults
1.7% of energy
significantly higher
#5
chickpea-supplemented diet
decrease
serum total cholesterol levels
-
-
results in lower
#6
chickpea-supplemented diet
decrease
low-density lipoprotein cholesterol levels
-
-
results in lower
#7
Abstract

AIM: To compare the effects of a chickpea-supplemented diet and those of a wheat-supplemented diet on human serum lipids and lipoproteins. METHODS: Forty-seven free-living adults participated in a randomized crossover weight maintenance dietary intervention involving two dietary periods, chickpea-supplemented and wheat-supplemented diets, each of at least 5 weeks duration. RESULTS: The serum total cholesterol and low-density lipoprotein cholesterol levels were significantly lower (both p < 0.01) by 3.9 and 4.6%, respectively, after the chickpea-supplemented diet as compared with the wheat-supplemented diet. Protein (0.9% of energy, p = 0.01) and monounsaturated fat (3.3% of total fat, p < 0.001) intakes were slightly but significantly lower and the carbohydrate intake significantly higher (1.7% of energy, p < 0.001) on the chickpea-supplemented diet as compared with the wheat-supplemented diet. Multivariate analyses suggested that the differences in serum lipids were mainly due to small differences in polyunsaturated fatty acid and dietary fibre contents between the two intervention diets. CONCLUSIONS: Inclusion of chickpeas in an intervention diet results in lower serum total and low-density lipoprotein cholesterol levels as compared with a wheat-supplemented diet.

Medical Subject Headings (MeSH)
AdsorptionAdultAgedCardiovascular DiseasesCholesterolCholesterol, LDLCicerCross-Over StudiesDietDiet RecordsDietary FiberDietary ProteinsDietary SupplementsFatty Acids, MonounsaturatedFatty Acids, UnsaturatedFemaleHumansHypercholesterolemiaLipidsMaleMiddle AgedTasmaniaTime FactorsTriticumVictoria
Study Links
Quality Scores
Safety90
Efficacy85/10
Quality80/10
Citation Metrics
Total Citations22
Citations/Year1.2
Relative Citation Ratio0.65
NIH Percentile35.1%
Research Impact Scores
APT Score0.50
Weight Score0.96
Normalized Score0.86
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