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Long-term follow-up of internet-delivered exposure and mindfulness based treatment for irritable bowel syndrome.

Behaviour research and therapy
January 1, 2011
Brjánn Ljótsson et al. (7 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to evaluate the long-term effects of internet-delivered CBT based on exposure and mindfulness for IBS patients.

Results Summary

Treatment gains were maintained at follow-up (15-18 months) with large effect sizes, including improvements in IBS symptoms, quality of life, and anxiety related to gastrointestinal symptoms. Adequate symptom relief was reported by 59% of the original sample, with more pronounced improvements in those who completed full treatment.

Population

IBS patients (75 participants from an original sample of 85).

Effective Dosage

Not specified

Duration

Mean follow-up of 16.4 months after treatment completion.

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
internet-delivered cognitive behavior therapy (CBT) for IBS, based on exposure and mindfulness exercises
decrease
IBS symptoms
participants from the original sample
within-group Cohen's d=0.78-1.11
treatment gains were maintained
#1
internet-delivered cognitive behavior therapy (CBT) for IBS, based on exposure and mindfulness exercises
increase
quality of life
participants from the original sample
within-group Cohen's d=0.78-1.11
treatment gains were maintained
#2
internet-delivered cognitive behavior therapy (CBT) for IBS, based on exposure and mindfulness exercises
decrease
anxiety related to gastrointestinal symptoms
participants from the original sample
within-group Cohen's d=0.78-1.11
treatment gains were maintained
#3
internet-delivered cognitive behavior therapy (CBT) for IBS, based on exposure and mindfulness exercises
decrease
symptoms
fifty participants (59% of the total original sample; 52% of the original treatment group participants and 65% of the original waiting list participants)
-
reported adequate relief of symptoms
#4
internet-delivered cognitive behavior therapy (CBT) for IBS, based on exposure and mindfulness exercises
increase
improvements
participants that had completed the full treatment
-
improvements at follow-up were more pronounced
#5
internet-delivered cognitive behavior therapy (CBT) for IBS, based on exposure and mindfulness exercises
increase
effects
IBS-patients
-
has long-term beneficial effects
#6
Abstract

We conducted a follow-up of a previously reported study of internet-delivered cognitive behavior therapy (CBT) for IBS, based on exposure and mindfulness exercises (Ljótsson et al. (2010). Internet-delivered exposure and mindfulness based therapy for irritable bowel syndrome - a randomized controlled trial. Behaviour Research and Therapy, 48, 531-539). Seventy-five participants from the original sample of 85 (88%) reported follow-up data at 15-18 months (mean 16.4 months) after completing treatment. The follow-up sample included participants from both the original study's treatment group and waiting list after it had been crossed over to treatment. Intention-to-treat analysis showed that treatment gains were maintained on all outcome measures, including IBS symptoms, quality of life, and anxiety related to gastrointestinal symptoms, with mainly large effect sizes (within-group Cohen's d=0.78-1.11). A total of fifty participants (59% of the total original sample; 52% of the original treatment group participants and 65% of the original waiting list participants) reported adequate relief of symptoms. Improvements at follow-up were more pronounced for the participants that had completed the full treatment and maintenance of improvement did not seem to be dependent on further treatment seeking. This study suggests that internet-delivered CBT based on exposure and mindfulness has long-term beneficial effects for IBS-patients.

Medical Subject Headings (MeSH)
AdultAnxietyCognitive Behavioral TherapyFemaleFollow-Up StudiesHumansImplosive TherapyIrritable Bowel SyndromeMaleMeditationQuality of LifeTherapy, Computer-Assisted
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality80/10
Citation Metrics
Total Citations78
Citations/Year5.6
Relative Citation Ratio3.06
NIH Percentile85.4%
Research Impact Scores
APT Score0.95
Weight Score1.47
Normalized Score0.70
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