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Effectiveness of light therapy for depression among active duty service members: A nonrandomized controlled pilot trial.

Complementary therapies in medicine
June 1, 2011
R Gregory Lande et al. (4 authors)
Controlled Clinical TrialJournal ArticleHuman StudyClinical
Study Details

Study Goal

The researchers aimed to investigate the effectiveness of light therapy as an augmentation treatment for depression in active duty service members.

Results Summary

The study found a significant reduction in depression scores over time for both groups, with a statistical trend suggesting greater reduction in the high-intensity light therapy group during the active phase of treatment. Post-treatment scores were significantly lower than baseline.

Population

Active duty service members deployed to a combat area with depression scores ≥50 on the Zung Self-Rating Depression Scale.

Effective Dosage

10,000 lux (treatment group) and 50 lux (control group) for 90 minutes daily.

Duration

Five consecutive days.

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
light therapy at 10,000 lux
decrease
depression scores
active duty service members deployed to an area of combat operations
null
showed a statistical trend for depression scores to be reduced
#1
light therapy at 10,000 lux
decrease
depression
active duty service members
null
hints at the possibility of a reduction in depression
#2
light therapy (combined groups)
decrease
depression scores
active duty service members
null
depression scores reduced over time
#3
light therapy (combined groups)
decrease
Zung score
active duty service members
null
post-treatment Zung score was significantly lower indicating less depression than the baseline Zung score
#4
Abstract

OBJECTIVE: The authors investigated the potential effectiveness of light therapy as an augmentation treatment for depression among active duty service members. DESIGN: This pilot study recruited active duty service members deployed to an area of combat operations. Enrollment was offered to service members scoring 50 or greater on the Zung Self-Rating Depression Scale. The authors implemented a systematic sampling technique randomly assigning the first subject and then alternating each subsequent subject to either a reference group which received the usual standard of care plus light therapy at 10,000 lux or a control group which received the usual standard of care and light therapy at 50 lux. Both groups received 90 min light sessions for five days. SETTING: The study was conducted at Walter Reed Army Medical Center's Psychiatry Continuity Service. MAIN OUTCOME MEASURE: Zung Self-Rating Depression Scale collected at baseline, after five consecutive daily light sessions, and one week later. RESULTS: A repeated measures analysis of variance (RM ANOVA) was conducted to examine the change in Zung Depression results which showed a significant main effect for time F(2, 21)=5.05, p<0.02, indicating that depression scores reduced over time for both participant groups. Post hoc comparisons (with Bonferroni correction) demonstrated that the post-treatment Zung score was significantly lower indicating less depression than the baseline Zung score (p<0.004) and there was a statistical trend (p<0.05) for depression scores to be reduced halfway through the study in the treatment group. CONCLUSION: The post hoc analysis hints at the possibility of a reduction in depression during the active phase of light treatment.

Medical Subject Headings (MeSH)
AdultAnalysis of VarianceDepressionDepressive DisorderFemaleHumansMaleMilitary PersonnelPhototherapyPilot ProjectsSeverity of Illness IndexStandard of CareTreatment OutcomeYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality75/10
Citation Metrics
Total Citations8
Citations/Year0.6
Relative Citation Ratio0.38
NIH Percentile20.2%
Research Impact Scores
APT Score0.25
Weight Score1.20
Normalized Score0.63
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