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Therapeutic mechanisms of a mindfulness-based treatment for IBS: effects on visceral sensitivity, catastrophizing, and affective processing of pain sensations.

Journal of behavioral medicine
December 1, 2012
Eric L Garland et al. (6 authors)
Journal ArticleRandomized Controlled TrialResearch Support, N.I.H., ExtramuralHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether mindfulness training (MT) could improve IBS symptoms by targeting affective pain processing and catastrophic appraisals of gastrointestinal sensations.

Results Summary

MT significantly improved IBS symptoms by reducing gut-focused anxiety and catastrophic appraisals of abdominal sensations while enhancing nonreactive awareness of interoceptive data with less emotional interference. The study suggests MT effectively targets underlying pathogenic mechanisms of IBS.

Population

75 female IBS patients

Effective Dosage

Not specified

Duration

8 weeks

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
mindfulness training (MT)
decrease
IBS symptoms
female IBS patients
-
exerts significant therapeutic effects
#1
mindfulness training (MT)
decrease
gut-focused anxiety
female IBS patients
-
promotes nonreactivity
#2
mindfulness training (MT)
decrease
catastrophic appraisals of the significance of abdominal sensations
female IBS patients
-
promotes nonreactivity
#3
mindfulness training (MT)
increase
interoceptive data with less emotional interference
female IBS patients
-
refocusing of attention
#4
mindfulness training (MT)
decrease
underlying pathogenic mechanisms of IBS
female IBS patients
-
target and ameliorate
#5
Abstract

Irritable bowel syndrome (IBS) is a prevalent functional disorder characterized by abdominal pain and hypervigilance to gastrointestinal sensations. We hypothesized that mindfulness training (MT), which promotes nonreactive awareness of emotional and sensory experience, may target underlying mechanisms of IBS including affective pain processing and catastrophic appraisals of gastrointestinal sensations. Seventy five female IBS patients were randomly assigned to participate in either 8 weeks of MT or a social support group. A theoretically grounded, multivariate path model tested therapeutic mediators of the effect of MT on IBS severity and quality of life. Results suggest that MT exerts significant therapeutic effects on IBS symptoms by promoting nonreactivity to gut-focused anxiety and catastrophic appraisals of the significance of abdominal sensations coupled with a refocusing of attention onto interoceptive data with less emotional interference. Hence, MT appears to target and ameliorate the underlying pathogenic mechanisms of IBS.

Medical Subject Headings (MeSH)
AdolescentAdultAffectAgedAnxietyAttentionCatastrophizationFemaleHumansIrritable Bowel SyndromeMiddle AgedMindfulnessPain ManagementQuality of LifeSeverity of Illness IndexYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality80/10
Citation Metrics
Total Citations138
Citations/Year10.6
Relative Citation Ratio5.54
NIH Percentile94.1%
Research Impact Scores
APT Score0.95
Weight Score1.63
Normalized Score0.70
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