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Long-term creatine supplementation improves muscular performance during resistance training in older women.

European journal of applied physiology
April 1, 2013
Andreo Fernando Aguiar et al. (8 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to compare the effects of creatine supplementation versus maltodextrin (placebo) combined with resistance training on strength, functional performance, and body composition in older women.

Results Summary

The maltodextrin (placebo) group showed no significant changes in body mass or % body fat and had lesser improvements in strength, functional performance, and muscle mass compared to the creatine group.

Population

Healthy older women (64.9 ± 5.0 years)

Effective Dosage

5.0 g day(-1)

Duration

12 weeks

Interactions

None mentioned

Extracted Claims (9)
InterventionDirectionEndpointPopulationDosageImpactClaim #
long-term creatine supplementation combined with resistance training
increase
training volume
older women
+164.2 Δ%
experienced a greater increase
#1
long-term creatine supplementation combined with resistance training
increase
1RM bench press performance
older women
+5.1 Δ%
experienced a greater increase
#2
long-term creatine supplementation combined with resistance training
increase
knee extension performance
older women
+3.9 Δ%
experienced a greater increase
#3
long-term creatine supplementation combined with resistance training
increase
biceps curl performance
older women
+8.8 Δ%
experienced a greater increase
#4
long-term creatine supplementation combined with resistance training
increase
fat-free mass
older women
+3.2
gained significantly more
#5
long-term creatine supplementation combined with resistance training
increase
muscle mass
older women
+2.8
gained significantly more
#6
long-term creatine supplementation combined with resistance training
increase
submaximal-strength functional tests
older women
-
were more efficient in performing
#7
long-term creatine supplementation combined with resistance training
no change
body mass
older women
-
No changes
#8
long-term creatine supplementation combined with resistance training
no change
% body fat
older women
-
No changes
#9
Abstract

This study examined the effects of long-term creatine supplementation combined with resistance training (RT) on the one-repetition maximum (1RM) strength, motor functional performance (e.g., 30-s chair stand, arm curl, and getting up from lying on the floor tests) and body composition (e.g., fat-free mass, muscle mass, and % body fat using DEXA scans) in older women. Eighteen healthy women (64.9 ± 5.0 years) were randomly assigned in a double-blind fashion to either a creatine (CR, N = 9) or placebo (PL, N = 9) group. Both groups underwent a 12-week RT program (3 days week(-1)), consuming an equivalent amount of either creatine (5.0 g day(-1)) or placebo (maltodextrin). After 12 week, the CR group experienced a greater (P < 0.05) increase (Δ%) in training volume (+164.2), and 1RM bench press (+5.1), knee extension (+3.9) and biceps curl (+8.8) performance than the PL group. Furthermore, CR group gained significantly more fat-free mass (+3.2) and muscle mass (+2.8) and were more efficient in performing submaximal-strength functional tests than the PL group. No changes (P > 0.05) in body mass or % body fat were observed from pre- to post-test in either group. These results indicate that long-term creatine supplementation combined with RT improves the ability to perform submaximal-strength functional tasks and promotes a greater increase in maximal strength, fat-free mass and muscle mass in older women.

Medical Subject Headings (MeSH)
Absorptiometry, PhotonAge FactorsAgedAnalysis of VarianceBody CompositionBrazilCreatineDietary SupplementsDouble-Blind MethodFemaleHumansMiddle AgedMotor ActivityMuscle ContractionMuscle StrengthMuscle, SkeletalOrgan SizePerformance-Enhancing SubstancesResistance TrainingSex FactorsTime Factors
Study Links
Quality Scores
SafetyNot Assessed
Efficacy20/10
Quality85/10
Citation Metrics
Total Citations64
Citations/Year5.3
Relative Citation Ratio2.96
NIH Percentile84.7%
Research Impact Scores
APT Score0.95
Weight Score1.72
Normalized Score0.45
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