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Osteoporosis diagnosis and medical treatment.

The Orthopedic clinics of North America
April 1, 2013
Amy H Warriner et al. (2 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the role of calcium and vitamin D in bone health and fracture prevention, particularly in the context of osteoporosis.

Results Summary

The study found that calcium and vitamin D remain important for bone health despite safety controversies, but prescription treatments should be considered for high-risk individuals. Several treatment options are available for fracture prevention.

Population

Individuals with osteoporosis (low bone mineral density or history of fragility fractures).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
nonpharmacologic treatments
decrease
fracture
-
-
fracture prevention is possible through use of
#1
prescription treatments
decrease
fracture
-
-
fracture prevention is possible through use of
#2
calcium supplementation
increase
bone health
-
-
remain an important part of
#3
vitamin D
increase
bone health
-
-
remain an important part of
#4
prescription osteoporosis treatments
decrease
fracture risk
those at higher risk for fracture
-
should be considered for
#5
Abstract

Osteoporosis, the presence of either low bone mineral density or a history of a fragility fracture, is known to be associated with an increased risk of future fracture. Fracture prevention is possible through use of both nonpharmacologic and prescription treatments. Despite recent controversy regarding the safety of calcium supplementation and the appropriate dosing of calcium and vitamin D, calcium and vitamin D remain an important part of bone health. However, prescription osteoporosis treatments should be considered for those at higher risk for fracture, and there are currently several treatment options available.

Medical Subject Headings (MeSH)
Antibodies, Monoclonal, HumanizedCalciumDenosumabDiphosphonatesHip FracturesHumansOsteoporosisOsteoporotic FracturesRANK LigandRecurrenceRisk AssessmentTeriparatideVitamin D
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality60/10
Citation Metrics
Total Citations21
Citations/Year1.8
Relative Citation Ratio0.72
NIH Percentile38.6%
Research Impact Scores
APT Score0.50
Weight Score1.29
Normalized Score0.60
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