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Vitamin D in the healthy European paediatric population.

Journal of pediatric gastroenterology and nutrition
June 1, 2013
Christian Braegger et al. (12 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to summarize data on vitamin D intake and deficiency in healthy European children, discuss its health benefits, and provide recommendations for preventing deficiency, with a focus on its role in calcium metabolism.

Results Summary

Vitamin D is essential for calcium and phosphate metabolism and bone health, but evidence for other health benefits in children is insufficient. Deficiency is common, especially in high-risk groups like breast-fed infants and obese children.

Population

Healthy European infants, children, and adolescents, particularly high-risk groups (e.g., breast-fed infants, dark-skinned individuals in northern countries, those with inadequate sun exposure, obese children).

Effective Dosage

400 IU/day for infants; supplementation beyond 1 year for high-risk groups.

Duration

Not specified

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
vitamin D supplementation
neutral
calcium and phosphate metabolism
-
-
plays a key role
#1
vitamin D supplementation
neutral
bone health
-
-
is essential for
#2
vitamin D supplementation
no change
other health benefits
infants, children, and adolescents
insufficient evidence
insufficient evidence to support
#3
oral supplementation of 400 IU/day of vitamin D
increase
vitamin D status
infants
400 IU/day
should receive
#4
oral supplementation of vitamin D
increase
vitamin D status
children in risk groups beyond 1 year of age
-
must be considered
#5
healthy lifestyle with varied diet and adequate outdoor activities
increase
vitamin D status
healthy children and adolescents
-
should be encouraged
#6
Abstract

In recent years, reports suggesting a resurgence of vitamin D deficiency in the Western world, combined with various proposed health benefits for vitamin D supplementation, have resulted in increased interest from health care professionals, the media, and the public. The aim of this position paper is to summarise the published data on vitamin D intake and prevalence of vitamin D deficiency in the healthy European paediatric population, to discuss the health benefits of vitamin D and to provide recommendations for the prevention of vitamin D deficiency in this population. Vitamin D plays a key role in calcium and phosphate metabolism and is essential for bone health. There is insufficient evidence from interventional studies to support vitamin D supplementation for other health benefits in infants, children, and adolescents. The pragmatic use of a serum concentration >50 nmol/L to indicate sufficiency and a serum concentration <25 nmol/L to indicate severe deficiency is recommended. Vitamin D deficiency occurs commonly among healthy European infants, children, and adolescents, especially in certain risk groups, including breast-fed infants, not adhering to the present recommendation for vitamin D supplementation, children and adolescents with dark skin living in northern countries, children and adolescents without adequate sun exposure, and obese children. Infants should receive an oral supplementation of 400 IU/day of vitamin D. The implementation should be promoted and supervised by paediatricians and other health care professionals. Healthy children and adolescents should be encouraged to follow a healthy lifestyle associated with a normal body mass index, including a varied diet with vitamin D-containing foods (fish, eggs, dairy products) and adequate outdoor activities with associated sun exposure. For children in risk groups identified above, an oral supplementation of vitamin D must be considered beyond 1 year of age. National authorities should adopt policies aimed at improving vitamin D status using measures such as dietary recommendations, food fortification, vitamin D supplementation, and judicious sun exposure, depending on local circumstances.

Medical Subject Headings (MeSH)
AdolescentAdolescent DevelopmentBone DevelopmentChildChild DevelopmentChild, PreschoolDietDietary SupplementsEuropeFood, FortifiedHealth PolicyHealth PromotionHumansInfantPractice Guidelines as TopicPrevalenceSocieties, ScientificSunlightVitamin DVitamin D Deficiency
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations316
Citations/Year26.3
Relative Citation Ratio14.07
NIH Percentile98.8%
Research Impact Scores
APT Score0.95
Weight Score1.91
Normalized Score0.67
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