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Delayed sleep phase disorder in youth.

Current opinion in psychiatry
November 1, 2013
Michael Gradisar et al. (2 authors)
Journal ArticleResearch Support, N.I.H., ExtramuralReviewHuman Study
Study Details

Study Goal

The researchers aimed to review the latest findings on the clinical features, causes, and treatments of delayed sleep phase disorder (DSPD), including the effectiveness of melatonin administration.

Results Summary

Evening melatonin administration as a sole treatment appears promising for DSPD, alongside cognitive-behavior therapy and morning bright light. The study highlights its potential in treating delayed circadian rhythm and sleep-onset insomnia.

Population

Adolescents and young adults with delayed sleep phase disorder (DSPD).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (2)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Evening melatonin administration
decrease
delayed sleep phase disorder (DSPD)
young people
-
appears promising
#1
combination of cognitive-behavior therapy and morning bright light
decrease
delayed sleep phase disorder (DSPD)
young people
-
appears promising
#2
Abstract

PURPOSE OF REVIEW: For over 30 years, delayed sleep phase disorder (DSPD) has been defined as a debilitating sleep condition. Recently, there is more awareness of DSPD in young people, yet considerable information is needed to understand its cause and treatment. This review describes the latest research findings describing the clinical features, cause, and treatment of DSPD. RECENT FINDINGS: The prevalence of DSPD in adolescents and young adults ranges from 1 to 16%. The impact on the individuals is significant, particularly in the domains of school/work performance and mental health. We describe various contributing factors including reduced homeostatic sleep pressure, a lengthened and delayed circadian rhythm, insensitivity to clock-resetting morning light, and heightened cognitive activity. Evening melatonin administration as a sole treatment appears promising, as is a combination of cognitive-behavior therapy and morning bright light. SUMMARY: Recent findings suggest clinicians to be aware of the clinical features (i.e., significant daytime sleepiness, anxiety and depression symptoms, potential for school dropout) of DSPD, as several biological features underpinning this disorder are unseen in clinical settings. We advise clinicians to become familiar with exogenous evening melatonin administration, and cognitive and behavioral techniques to simultaneously treat the delayed circadian rhythm and associated sleep-onset insomnia.

Medical Subject Headings (MeSH)
AdolescentCentral Nervous System DepressantsHumansPhototherapyPsychotherapySleep Disorders, Circadian RhythmVitamin B 12Young Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy80/10
Quality75/10
Citation Metrics
Total Citations54
Citations/Year4.5
Relative Citation Ratio2.37
NIH Percentile79.4%
Research Impact Scores
APT Score0.75
Weight Score1.57
Normalized Score0.67
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