Massage therapy for fibromyalgia: a systematic review and meta-analysis of randomized controlled trials.
Study Goal
The researchers aimed to evaluate the evidence of massage therapy for improving pain, anxiety, depression, and sleep disturbance in patients with fibromyalgia.
Results Summary
Massage therapy lasting ≥5 weeks significantly improved pain, anxiety, and depression in fibromyalgia patients but did not significantly affect sleep disturbance. The study concluded that massage therapy is a viable complementary treatment for fibromyalgia, though larger trials with longer follow-up are needed.
Population
Patients with fibromyalgia (404 participants across 9 randomized controlled trials).
Effective Dosage
Not specified (duration ≥5 weeks mentioned).
Duration
≥5 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
massage therapy with duration ≥ 5 weeks | decrease | pain | patients with FM | SMD, 0.62; 95% CI 0.05 to 1.20; p = 0.03 | significantly improved | #1 |
massage therapy with duration ≥ 5 weeks | decrease | anxiety | patients with FM | SMD, 0.44; 95% CI 0.09 to 0.78; p = 0.01 | significantly improved | #2 |
massage therapy with duration ≥ 5 weeks | decrease | depression | patients with FM | SMD, 0.49; 95% CI 0.15 to 0.84; p = 0.005 | significantly improved | #3 |
massage therapy | no change | sleep disturbance | patients with FM | SMD, 0.19; 95% CI -0.38 to 0.75; p = 0.52 | had no effect on | #4 |
BACKGROUND: Although some studies evaluated the effectiveness of massage therapy for fibromyalgia (FM), the role of massage therapy in the management of FM remained controversial. OBJECTIVE: The purpose of this systematic review is to evaluate the evidence of massage therapy for patients with FM. METHODS: Electronic databases (up to June 2013) were searched to identify relevant studies. The main outcome measures were pain, anxiety, depression, and sleep disturbance. Two reviewers independently abstracted data and appraised risk of bias. The risk of bias of eligible studies was assessed based on Cochrane tools. Standardised mean difference (SMD) and 95% confidence intervals (CI) were calculated by more conservative random-effects model. And heterogeneity was assessed based on the I(2) statistic. RESULTS: Nine randomized controlled trials involving 404 patients met the inclusion criteria. The meta-analyses showed that massage therapy with duration ≥ 5 weeks significantly improved pain (SMD, 0.62; 95% CI 0.05 to 1.20; p = 0.03), anxiety (SMD, 0.44; 95% CI 0.09 to 0.78; p = 0.01), and depression (SMD, 0.49; 95% CI 0.15 to 0.84; p = 0.005) in patients with FM, but not on sleep disturbance (SMD, 0.19; 95% CI -0.38 to 0.75; p = 0.52). CONCLUSION: Massage therapy with duration ≥ 5 weeks had beneficial immediate effects on improving pain, anxiety, and depression in patients with FM. Massage therapy should be one of the viable complementary and alternative treatments for FM. However, given fewer eligible studies in subgroup meta-analyses and no evidence on follow-up effects, large-scale randomized controlled trials with long follow-up are warrant to confirm the current findings.