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Mindfulness-based cognitive therapy for people with diabetes and emotional problems: long-term follow-up findings from the DiaMind randomized controlled trial.

Journal of psychosomatic research
July 1, 2014
Jenny van Son et al. (6 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine if the benefits of mindfulness-based cognitive therapy (MBCT) on emotional distress in people with diabetes would be sustained six months after the intervention.

Results Summary

MBCT showed sustained reductions in perceived stress, anxiety, and depressive symptoms (HADS) at six-month follow-up, but no significant effects on diabetes distress or HbA1c. The effects were statistically significant with moderate to large effect sizes, though POMS depressive symptoms did not remain significant after multiple testing correction.

Population

139 outpatients with diabetes (type-I or type-II) and lowered emotional well-being.

Effective Dosage

Not specified

Duration

Not specified (follow-up was six months post-intervention)

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
mindfulness-based cognitive therapy (MBCT)
decrease
perceived stress
outpatients with diabetes (type-I or type-II) and a lowered level of emotional well-being
p<.001, d=.76
showed sustained reductions
#1
mindfulness-based cognitive therapy (MBCT)
decrease
anxiety (assessed by HADS)
outpatients with diabetes (type-I or type-II) and a lowered level of emotional well-being
p<.001, d=.83
showed sustained reductions
#2
mindfulness-based cognitive therapy (MBCT)
decrease
anxiety (assessed by POMS)
outpatients with diabetes (type-I or type-II) and a lowered level of emotional well-being
p<.001, d=.92
showed sustained reductions
#3
mindfulness-based cognitive therapy (MBCT)
decrease
HADS depressive symptoms
outpatients with diabetes (type-I or type-II) and a lowered level of emotional well-being
p=.004, d=.51
showed sustained reductions
#4
mindfulness-based cognitive therapy (MBCT)
no change
POMS depressive symptoms
outpatients with diabetes (type-I or type-II) and a lowered level of emotional well-being
p=.016, d=.48
showed no significant between-group effect
#5
mindfulness-based cognitive therapy (MBCT)
no change
diabetes distress
outpatients with diabetes (type-I or type-II) and a lowered level of emotional well-being
-
showed no significant between-group effect
#6
mindfulness-based cognitive therapy (MBCT)
no change
HbA1c
outpatients with diabetes (type-I or type-II) and a lowered level of emotional well-being
-
showed no significant between-group effect
#7
Abstract

OBJECTIVE: The DiaMind trial showed beneficial immediate effects of mindfulness-based cognitive therapy (MBCT) on emotional distress, but not on diabetes distress and HbA1c. The aim of the present report was to examine if the effects would be sustained after six month follow-up. METHODS: In the DiaMind trial, 139 outpatients with diabetes (type-I or type-II) and a lowered level of emotional well-being were randomized into MBCT (n=70) or a waiting list with treatment as usual (TAU: n=69). Primary outcomes were perceived stress, anxiety and depressive symptoms, and diabetes distress. Secondary outcomes were, among others, health status, and glycemic control (HbA1c). RESULTS: Compared to TAU, MBCT showed sustained reductions at follow-up in perceived stress (p<.001, d=.76), anxiety (p<.001, assessed by HADS d=.83; assessed by POMS d=.92), and HADS depressive symptoms (p=.004, d=.51), but not POMS depressive symptoms when using Bonferroni correction for multiple testing (p=.016, d=.48). No significant between-group effect was found on diabetes distress and HbA1c. CONCLUSION: This study showed sustained benefits of MBCT six months after the intervention on emotional distress in people with diabetes and a lowered level of emotional well-being. TRIAL REGISTRATION: Dutch Trial Register NTR2145, http://www.trialregister.nl.

Medical Subject Headings (MeSH)
AdultAnxiety DisordersDepressionDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2EmotionsFemaleFollow-Up StudiesHumansMaleMental HealthMiddle AgedMindfulnessOutpatientsStress, PsychologicalWaiting ListsCognitive Behavioral Therapy
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations52
Citations/Year4.7
Relative Citation Ratio2.39
NIH Percentile79.6%
Research Impact Scores
APT Score0.95
Weight Score1.81
Normalized Score0.67
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