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The use of low-carbohydrate diet in type 2 diabetes - benefits and risks.

Annals of agricultural and environmental medicine : AAEM
January 1, 2014
Łucja Czyżewska-Majchrzak et al. (5 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to identify the potential benefits and risks of a low-carbohydrate diet in patients with type 2 diabetes.

Results Summary

The study found that a low-carbohydrate diet positively affected blood glucose, glycosylated hemoglobin, and reduced insulin use, while also improving body weight and lipid profiles. However, it also noted risks such as mineral deficiencies, renal dysfunction, and adverse changes in markers predisposing to atherosclerosis.

Population

Patients with type 2 diabetes.

Effective Dosage

Not Assessed

Duration

Short-term (exact duration not specified)

Interactions

None mentioned

Extracted Claims (13)
InterventionDirectionEndpointPopulationDosageImpactClaim #
low-carbohydrate diet
decrease
concentration of blood glucose
patients with type 2 diabetes
-
affects positively
#1
low-carbohydrate diet
decrease
glycosylated haemoglobin
patients with type 2 diabetes
-
affects positively
#2
low-carbohydrate diet
decrease
insulin taken in the course of drug therapy
patients with type 2 diabetes
-
contributes to the reduction
#3
low-carbohydrate diet
decrease
body weight
patients with type 2 diabetes
-
positive relationship with reduction
#4
low-carbohydrate diet
increase
lipid profile of HDL cholesterol
patients with type 2 diabetes
-
favourable changes
#5
low-carbohydrate diet
decrease
levels of triglyceride
patients with type 2 diabetes
-
favourable changes
#6
low-carbohydrate diet
increase
mineral deficiency
patients with type 2 diabetes
-
increased risk
#7
low-carbohydrate diet
increase
hypovitaminosis
patients with type 2 diabetes
-
increased risk
#8
low-carbohydrate diet
decrease
dietary fibres
patients with type 2 diabetes
-
reduced intake
#9
low-carbohydrate diet
increase
renal dysfunction
patients with type 2 diabetes
-
raises the risk
#10
low-carbohydrate diet
increase
irregularities in the water and electrolyte balance
patients with type 2 diabetes
-
raises the risk
#11
low-carbohydrate diet
increase
development of osteopenia and osteoporosis
patients with type 2 diabetes
-
impact of changes
#12
low-carbohydrate diet
increase
adverse changes in other markers predisposing to atherosclerosis
individuals with type 2 diabetes
-
significantly increases the risk
#13
Abstract

The pharmacological treatment of type 2 diabetes is increasingly being supported by the recommendation of an appropriate diet. The purpose of this study is to identify the potential benefits and risks arising from the use of one of the modern models of low-carbohydrate diet in patients with type 2 diabetes. Research shows that diet can favourably affect the health of diabetic patients. It has been shown that diet affects positively the concentration of blood glucose, glycosylated haemoglobin, and also contributes to the reduction of insulin taken in the course of drug therapy. At the same time, short-term studies have demonstrated a positive relationship of nutrition with reduction in body weight, as well as favourable changes in lipid profile of HDL cholesterol and levels of triglyceride. Attention is also drawn to the negative health effects of a low-carbohydrate diet; these include an increased risk of mineral deficiency, hypovitaminosis and reduced intake of dietary fibres. This diet may be associated with very high levels of protein which, in turn, raises the risk of renal dysfunction and the appearance of irregularities in the water and electrolyte balance. The impact of changes in the skeletal system and the development of osteopenia and osteoporosis is also observed. Besides the positive impact of this model of diet on the lipid profile parameters, its use significantly increases the risk of adverse changes in other markers predisposing to atherosclerosis occurring in individuals with type 2 diabetes. In composing a nutrition model for diabetes patients, both the benefits and potential risks of a low-carbohydrate diet should therefore take into account. At the same time, it is important to individualize the diet used, based on the current state of health, used pharmacological treatments, as well as taking into account the individual characteristics of the patient.

Medical Subject Headings (MeSH)
Diabetes Mellitus, Type 2Diet, Carbohydrate-RestrictedHumansRisk Assessment
Study Links
Quality Scores
Safety60
Efficacy75/10
Quality70/10
Citation Metrics
Total Citations14
Citations/Year1.3
Relative Citation Ratio0.54
NIH Percentile29.5%
Research Impact Scores
APT Score0.75
Weight Score1.46
Normalized Score0.68
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