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Facial rejuvenation: combining cosmeceuticals with cosmetic procedures.

Cutis
September 1, 2014
Joy D Wisniewski et al. (3 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the role of antioxidants in cosmeceuticals as adjunctive therapies to enhance cosmetic procedures and reduce postprocedural inflammation and healing time.

Results Summary

The study found that antioxidants, when combined with anti-inflammatories in cosmeceuticals, can help reduce postprocedure inflammation. They also noted that topical retinoids and hyaluronic acid contribute to faster healing and noninvasive antiaging effects.

Population

Cosmetic patients seeking antiaging treatments, including those undergoing chemical peels, lasers, and injectables.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Adjunctive agents
increase
chemical peels
-
-
can be used to enhance
#1
Adjunctive agents
decrease
postinflammatory hyperpigmentation (PIH)
-
-
decrease
#2
Topical retinoids used prior to ablative laser treatments
increase
postprocedure healing and reepithelialization
-
-
can aid in faster
#3
Cosmeceuticals that contain both antioxidants and anti-inflammatories
decrease
postprocedure inflammation
-
-
can help reduce
#4
Acetyl hexapeptide-3
decrease
wrinkles
-
-
is an effective topical agent for decreasing
#5
Acetyl hexapeptide-3 used as an adjunct to intramuscular botulinum neurotoxin
decrease
the number of injections needed
-
-
may reduce
#6
Abstract

Cosmetic patients are looking for a more youthful appearance without spending a lot of money, feeling any pain, or experiencing any postprocedure downtime. New cosmeceutical therapies can be used adjuvant to chemical peels, lasers, and injectables, making antiaging regimens less painful and requiring less postprocedural healing time. Adjunctive agents can be used to enhance chemical peels and decrease postinflammatory hyperpigmentation (PIH). Topical retinoids used prior to ablative laser treatments can aid in faster postprocedure healing and reepithelialization. Cosmeceuticals that contain both antioxidants and anti-inflammatories can help reduce postprocedure inflammation. Acetyl hexapeptide-3 is an effective topical agent for decreasing wrinkles and can be used as an adjunct to intramuscular botulinum neurotoxin, which may reduce the number of injections needed. Topical hyaluronic acid also would help patients who are averse to needles or are just starting to get wrinkles and are looking for noninvasive therapy. This article reviews combinations of cosmeceuticals with cosmetic procedures that dermatologists may want to consider discussing with their cosmetic patients.

Medical Subject Headings (MeSH)
Combined Modality TherapyCosmetic TechniquesDermatologic AgentsHumansLow-Level Light TherapyRejuvenationSkin Aging
Study Links
PubMed ID25279473
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality60/10
Citation Metrics
Total Citations4
Citations/Year0.4
Relative Citation Ratio0.30
NIH Percentile15.5%
Research Impact Scores
APT Score0.25
Weight Score1.23
Normalized Score0.62
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