Current evidence on the health-beneficial effects of berry fruits in the prevention and treatment of metabolic syndrome.
Study Goal
The researchers aimed to evaluate the health benefits of berries, rich in antioxidants and bioactive compounds, in preventing and treating metabolic diseases such as obesity, hypertension, type 2 diabetes, dyslipidemia, and nonalcoholic fatty liver disease.
Results Summary
The study found that berry consumption improves hepatic function, increases insulin sensitivity and HDL-cholesterol, reduces serum glucose and LDL-cholesterol, and is inversely associated with type 2 diabetes incidence. Long-term berry intake may delay metabolic syndrome progression.
Population
Animal and human studies (epidemiological and interventional).
Effective Dosage
Not specified.
Duration
Not specified.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
berries | neutral | human health and prevention of diseases | human | - | exert a synergistic and cumulative effect on promotion | #1 |
berries | increase | hepatic function | human participants | - | beneficial effects on | #2 |
berry diet rich in antioxidants and bioactive phytochemicals | increase | insulin sensitivity | human participants | - | increase of | #3 |
berry diet rich in antioxidants and bioactive phytochemicals | increase | high-density lipoprotein-cholesterol | human participants | - | increase of | #4 |
berry diet rich in antioxidants and bioactive phytochemicals | decrease | serum glucose | human participants | - | decrease of | #5 |
berry diet rich in antioxidants and bioactive phytochemicals | decrease | low-density lipoprotein-cholesterol | human participants | - | decrease of | #6 |
berries | decrease | type 2 diabetes | - | - | inversely associated with the incidence of | #7 |
berries | decrease | metabolic disorders | - | - | provide great benefits in preventing or mitigating | #8 |
regular long-term consumption of different berries | decrease | metabolic syndrome and comorbidities | - | - | could potentially delay the progression of | #9 |
PURPOSE OF REVIEW: Berries belong to the best dietary sources of bioactive compounds, which exert a synergistic and cumulative effect on promotion of human health and prevention of diseases. The present review presents the most recent findings of animal and human studies regarding the health benefits of berries in terms of prevention and treatment of obesity, hypertension, type 2 diabetes, dyslipidemia, and nonalcoholic fatty liver disease. RECENT FINDINGS: In the last years, there was a growing number of evidence from human epidemiological and interventional studies, which emphasized the role of berries in the management of metabolic diseases. Based on the results from recent clinical trials, it can be established that a berry diet rich in antioxidants and bioactive phytochemicals has beneficial effects on hepatic function, increase of insulin sensitivity and high-density lipoprotein-cholesterol, decrease of serum glucose and low-density lipoprotein-cholesterol, and finally is inversely associated with the incidence of type 2 diabetes. SUMMARY: Numerous recent studies have shown that berries provide great benefits in preventing or mitigating metabolic disorders. The results of this review indicate that regular long-term consumption of different berries could potentially delay the progression of metabolic syndrome and comorbidities.