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A multicenter randomized controlled trial for bright light therapy in adults with intellectual disabilities and depression: Study protocol and obstacle management.

Research in developmental disabilities
January 1, 2017
Pauline C M Hamers et al. (3 authors)
Journal ArticleMulticenter StudyRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine the feasibility and potential effectiveness of bright light therapy (BLT) for treating depression in adults with intellectual disabilities (ID).

Results Summary

The abstract does not report specific results but highlights the need for a multicenter randomized controlled trial (RCT) to study BLT's antidepressant effects in adults with ID.

Population

Adults with intellectual disabilities (ID)

Effective Dosage

Not available

Duration

Not specified

Interactions

None mentioned

Extracted Claims (3)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Bright light therapy (BLT)
decrease
depression
the general population
-
is an effective intervention
#1
Bright light therapy (BLT)
decrease
seasonal depression
the general population
-
is an effective intervention
#2
Bright light therapy (BLT)
decrease
non-seasonal depression
the general population
-
is an effective intervention
#3
Abstract

Due to the limited cognitive and communicative abilities of adults with intellectual disabilities (ID), current treatment options for depression are often limited to lifestyle changes and pharmacological treatment. Bright light therapy (BLT) is an effective intervention for both seasonal and non-seasonal depression in the general population. BLT is an inexpensive, easy to carry out intervention with minimal side effects. However, knowledge on its anti-depressant effect in adults with ID is lacking. Obstacles in realizing a controlled intervention study in this particular study population may have contributed to this lack. To study the effect of BLT on depression in this population, it is necessary to successfully execute a multicenter randomized controlled trial (RCT). Therefore, the study protocol and the management of anticipated obstacles regarding this trial are presented.

Medical Subject Headings (MeSH)
ActigraphyAdultCircadian RhythmDepressionDepressive Disorder, MajorHairHumansHydrocortisoneIntellectual DisabilityMelatoninPhototherapySalivaStress, Psychological
Study Links
Quality Scores
Safety80
Quality70/10
Citation Metrics
Total Citations7
Citations/Year0.9
Relative Citation Ratio0.45
NIH Percentile24.1%
Research Impact Scores
APT Score0.50
Weight Score1.70
Normalized Score0.66
Related Supplements
A multicenter randomized controlled trial for bright light t... | Panacea Index