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Diet and lifestyle intervention on chronic moderate to severe depression and anxiety and other chronic conditions.

Complementary therapies in clinical practice
November 1, 2017
Gary Null et al. (2 authors)
Clinical TrialJournal ArticleHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether an intervention combining diet, exercise, lifestyle modification, and mindfulness techniques could improve chronic moderate to severe depression and anxiety in adults.

Results Summary

The study found that the majority of participants reported substantial improvements in depression, anxiety, and other conditions, with benefits persisting at a six-month follow-up. The results suggest that mindfulness, as part of a broader intervention, may provide considerable benefits for these conditions.

Population

500 adult men and women diagnosed with chronic moderate to severe depression and anxiety.

Effective Dosage

Not specified

Duration

12 weeks

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
diet, lifestyle and behavior modification, including a plant-based diet, daily exercise and mindfulness techniques
decrease
depression
500 adult men and women participants diagnosed with chronic moderate to severe depression and anxiety and other conditions
-
improvements
#1
diet, lifestyle and behavior modification, including a plant-based diet, daily exercise and mindfulness techniques
decrease
anxiety
500 adult men and women participants diagnosed with chronic moderate to severe depression and anxiety and other conditions
-
improvements
#2
diet, lifestyle and behavior modification, including a plant-based diet, daily exercise and mindfulness techniques
decrease
all other conditions addressed by the study
500 adult men and women participants diagnosed with chronic moderate to severe depression and anxiety and other conditions
-
improvements
#3
diet, lifestyle and behavior modification, including a plant-based diet, daily exercise and mindfulness techniques
decrease
depression, anxiety and all other conditions
the majority of participants
-
substantial benefits
#4
diet, lifestyle and behavior modification, including a plant-based diet, daily exercise and mindfulness techniques
decrease
depression, anxiety and other conditions
most of the participants
-
benefits persisted
#5
Abstract

This group study explored how an intervention of diet, lifestyle and behavior modification, including a plant-based diet, daily exercise and mindfulness techniques, would affect 500 adult men and women participants diagnosed with chronic moderate to severe depression and anxiety and other conditions during a 12 week period. An analysis of the health outcomes detailed in self-reported diary entries was carried out at the conclusion of the 12 week period. These reports noted improvements in depression, anxiety and all other conditions addressed by the study, with the majority of participants reporting substantial benefits. A six month follow up indicated that these benefits persisted in most of the participants. These results demonstrate that an intervention of diet, exercise, lifestyle and behavior modification may provide considerable benefits for moderate to severe depression and anxiety as well as other conditions.

Medical Subject Headings (MeSH)
AdultAnxiety DisordersChronic DiseaseDepressive DisorderDiet, VegetarianExerciseFemaleHealthy LifestyleHumansMaleMiddle AgedMindfulness
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations21
Citations/Year2.6
Relative Citation Ratio1.18
NIH Percentile56.3%
Research Impact Scores
APT Score0.75
Weight Score1.92
Normalized Score0.69
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