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Methods and procedures for: A randomized double-blind study investigating dose-dependent longitudinal effects of vitamin D supplementation on bone health.

Contemporary clinical trials
April 1, 2018
Lauren A Burt et al. (7 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether vitamin D supplementation above the Dietary Reference Intake (DRI) has dose-dependent effects on bone health.

Results Summary

The abstract does not provide results regarding Calcium's effects.

Population

Not specified in the abstract.

Effective Dosage

Not specified in the abstract.

Duration

Three years.

Interactions

None mentioned.

Extracted Claims (1)
InterventionDirectionEndpointPopulationDosageImpactClaim #
vitamin D supplementation
neutral
bone health
-
-
dose-dependent effects
#1
Abstract

The optimum dose of vitamin D and corresponding serum 25-hydroxyvitamin D (25OHD) concentration for bone health is still debated and some health practitioners are recommending doses well above the Canada/USA recommended Dietary Reference Intake (DRI). We designed a three-year randomized double-blind clinical trial investigating whether there are dose-dependent effects of vitamin D supplementation above the Dietary Reference Intake (DRI) on bone health. The primary aims of this study are to assess, whether supplementation of vitamin D

Medical Subject Headings (MeSH)
Absorptiometry, PhotonAgedBiological AvailabilityBone DensityBone and BonesDietary SupplementsDose-Response Relationship, DrugFemaleHumansMaleMiddle AgedPrimary PreventionTomography, X-Ray ComputedVitamin DVitamins
Study Links
Quality Scores
SafetyNot Assessed
Quality85/10
Citation Metrics
Total Citations10
Citations/Year1.4
Relative Citation Ratio0.56
NIH Percentile30.6%
Research Impact Scores
APT Score0.75
Weight Score2.10
Normalized Score0.57
Related Supplements
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