Management of bone health in patients with celiac disease: Practical guide for clinicians.
Study Goal
The researchers aimed to evaluate the impact of celiac disease on bone health and provide guidance on monitoring and managing bone health in these patients, including the role of a gluten-free diet.
Results Summary
The study found that celiac disease negatively affects bone health due to inflammation and malabsorption of calcium and vitamin D. A strict gluten-free diet, along with calcium and vitamin D supplementation and weight-bearing exercises, was recommended to improve bone health.
Population
Adults and children with celiac disease.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
inflammatory process and malabsorption of calcium and vitamin D | decrease | bone health | adults and children with celiac disease | - | negatively affected | #1 |
symptomatic celiac disease at diagnosis | decrease | bone mass | most adults | - | have low | #2 |
supplementation with calcium and vitamin D | neutral | - | patients with celiac disease | - | should be provided | #3 |
weight-bearing exercises | neutral | - | patients with celiac disease | - | encouraged | #4 |
adequate calcium and vitamin D supplementation | neutral | - | patients with celiac disease | - | require | #5 |
OBJECTIVE: To describe clinical issues related to bone health in patients with celiac disease (CD) and to provide guidance on monitoring bone health in these patients. SOURCES OF INFORMATION: A PubMed search was conducted to review literature relevant to CD and bone health, including guidelines published by professional gastroenterological organizations. MAIN MESSAGE: Bone health can be negatively affected in both adults and children with CD owing to the inflammatory process and malabsorption of calcium and vitamin D. Most adults with symptomatic CD at diagnosis have low bone mass. Bone mineral density should be tested at diagnosis and at follow-up, especially in adult patients. Vitamin D levels should be measured at diagnosis and annually until they are normal. In addition to a strict gluten-free diet, supplementation with calcium and vitamin D should be provided and weight-bearing exercises encouraged. CONCLUSION: Bone health can be adversely affected in patients with CD. These patients require adequate calcium and vitamin D supplementation, as well as monitoring of vitamin D levels and bone mineral density with regular follow-up to help prevent osteoporosis and fractures.