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Two-Week Exclusive Supplementation of Modified Ketogenic Nutrition Drink Reserves Lean Body Mass and Improves Blood Lipid Profile in Obese Adults: A Randomized Clinical Trial.

Nutrients
January 1, 1970
Hae-Ryeon Choi et al. (4 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to investigate the effects of two-week low-calorie ketogenic nutrition drinks on body weight, body composition, blood lipid profile, and blood ketone bodies in obese adults.

Results Summary

The study found that blood ketone bodies were induced and maintained in groups consuming both 4:1 and 1.7:1 ketogenic drinks, suggesting efficacy in achieving ketosis. Changes in body weight, body composition, and blood lipid profile were also investigated, though specific results were not detailed in the abstract.

Population

Obese adults

Effective Dosage

Ketone-to-non-ketone ratios of 4:1 (KD 4:1) and 1.7:1 (KD 1.7:1)

Duration

Two weeks

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
low-calorie ketogenic nutrition drinks
neutral
body weight
obese adults
-
investigated the effects
#1
low-calorie ketogenic nutrition drinks
neutral
body composition
obese adults
-
investigated the effects
#2
low-calorie ketogenic nutrition drinks
neutral
blood lipid profile
obese adults
-
investigated the effects
#3
low-calorie ketogenic nutrition drinks
neutral
blood ketone bodies
obese adults
-
investigated the effects
#4
ketogenic drink with a ketone-to-non-ketone ratio of 4:1 (KD 4:1)
increase
blood ketone bodies
obese adults
-
induced and maintained
#5
ketogenic drink partially complemented with protein at 1.7:1 (KD 1.7:1)
increase
blood ketone bodies
obese adults
-
induced and maintained
#6
Abstract

The ketogenic diet has long been recommended in patients with neurological disorders, and its protective effects on the cardiovascular system are of growing research interest. This study aimed to investigate the effects of two-week of low-calorie ketogenic nutrition drinks in obese adults. Subjects were randomized to consume drinks either a ketone-to-non-ketone ratio of 4:1 (KD 4:1), a drink partially complemented with protein at 1.7:1 (KD 1.7:1), or a balanced nutrition drink (BD). Changes in body weight, body composition, blood lipid profile, and blood ketone bodies were investigated. Blood ketone bodies were induced and maintained in the group that consumed both 4:1 and 1.7:1 ketogenic drinks (

Medical Subject Headings (MeSH)
AdultBeveragesBody CompositionDiet, KetogenicFemaleHumansLipidsMaleObesityYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Citation Metrics
Total Citations30
Citations/Year4.3
Relative Citation Ratio1.53
NIH Percentile65.8%
Research Impact Scores
APT Score0.75
Weight Score1.79
Normalized Score0.66
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