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Circadian Rhythm Sleep-Wake Phase Disorders.

Neurologic clinics
August 1, 2019
Elizabeth Culnan et al. (3 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers reviewed treatment options for delayed and advanced sleep-wake phase disorders, including melatonin administration.

Results Summary

The abstract mentions melatonin as a treatment option for sleep-wake phase disorders but does not provide specific efficacy data. Future directions are discussed, but no detailed results are given.

Population

Individuals with delayed or advanced sleep-wake phase disorders.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (3)
InterventionDirectionEndpointPopulationDosageImpactClaim #
gradual, daily shifting of the sleep schedule (chronotherapy)
neutral
delayed and advanced sleep-wake phase disorders
-
-
Treatment options include
#1
shifting circadian phase with properly timed light exposure (phototherapy)
neutral
delayed and advanced sleep-wake phase disorders
-
-
Treatment options include
#2
melatonin administration
neutral
delayed and advanced sleep-wake phase disorders
-
-
Treatment options include
#3
Abstract

This article reviews delayed and advanced sleep-wake phase disorders. Diagnostic procedures include a clinical interview to verify the misalignment of the major nocturnal sleep episode relative to the desired and social-normed timing of sleep, a 3-month or greater duration of the sleep-wake disturbance, and at least a week of sleep diary data consistent with the sleep timing complaint. Treatment options include gradual, daily shifting of the sleep schedule (chronotherapy); shifting circadian phase with properly timed light exposure (phototherapy); or melatonin administration. Future directions are discussed to conclude the article.

Medical Subject Headings (MeSH)
Circadian RhythmHumansMelatoninPhototherapySleep Disorders, Circadian Rhythm
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality60/10
Citation Metrics
Total Citations22
Citations/Year3.7
Relative Citation Ratio1.36
NIH Percentile61.6%
Research Impact Scores
APT Score0.75
Weight Score1.94
Normalized Score0.60
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