The association between low-carbohydrate diet score and metabolic syndrome among Iranian adults.
Study Goal
The researchers aimed to assess the relationship between adherence to a low-carbohydrate diet (LCD) and the prevalence of metabolic syndrome (Mets) in Iranian adults.
Results Summary
Higher adherence to LCD was associated with a significantly lower chance of Mets, particularly in men, and reduced abdominal obesity and low HDL cholesterol levels. The study found inverse relationships between LCD score and Mets components.
Population
Iranian adults (2074 participants from the Yazd Health Study and Taghzieh Mardom-e-Yazd study).
Effective Dosage
Not specified (LCD score calculated based on deciles of energy percentages from macronutrients).
Duration
Not specified (cross-sectional study).
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
low-carbohydrate diet (LCD) | decrease | metabolic syndrome (Mets) | all participants | OR: 0.68, 95% CI (0.50, 0.92) | had a significant lower chance of | #1 |
low-carbohydrate diet (LCD) | decrease | metabolic syndrome (Mets) | men | OR: 0.54, 95% CI (0.34, 0.86) | had a significant lower chance of | #2 |
low-carbohydrate diet (LCD) | decrease | metabolic syndrome (Mets) | women | OR: 0.53, 95% CI (0.34, 0.82) | had a significant lower chance of | #3 |
low-carbohydrate diet (LCD) | decrease | abdominal obesity | men | by 47% (OR: 0.53, 95% CI (0.28, 0.99)) | reduced | #4 |
low-carbohydrate diet (LCD) | decrease | low HDL cholesterol | all participants | OR: 0.74, 95% CI: 0.56-0.99 | significant inverse relation was observed between | #5 |
low-carbohydrate diet (LCD) | decrease | low HDL cholesterol | men | OR: 0.63, 95% CI: 0.40-0.98 | significant inverse relation was observed between | #6 |
OBJECTIVE: Assessing the relationship between low-carbohydrate diet (LCD) score and metabolic syndrome (Mets) in Iranian adults. DESIGN: Cross-sectional study. SETTING: Yazd Health Study and Taghzieh Mardom-e-Yazd study. PARTICIPANTS: Data of 2074 participants were used. Dietary intakes were assessed by a validated semi-quantitative FFQ. LCD score was calculated for each person by summing up the assigned scores to deciles of energy percentages from macronutrients. Mets was evaluated using National Cholesterol Education Program Adult Treatment Panel III. Eventually, association between LCD score and Mets was examined using logistic regression. RESULTS: Total Mets prevalence was approximately 40·5 %. After adjustment for confounders, subjects in the higher quartile of LCD score had a significant lower chance of Mets than lower quartile among all participants (Q4 v. Q1: OR: 0·68, 95 % CI (0·50, 0·92)) and separately in men (Q4 v. Q1: OR: 0·54, 95 % CI (0·34, 0·86)) and women (Q2 v. Q1: OR: 0·53, 95 % CI (0·34, 0·82)). Furthermore, more LCD adherence in men reduced abdominal obesity by 47 % (Q3 v. Q1: OR: 0·53, 95 % CI (0·28, 0·99)). A significant inverse relation was also observed between low HDL cholesterol and LCD score in all participants (Q4 versus Q1 OR: 0·74, 95% CI: 0·56-0·99) and separately in men (Q4 versus Q1 OR: 0·63, 95% CI: 0·40-0·98). CONCLUSIONS: More adherence to LCD might be related to lower chance of Mets and some of its components such as low HDL-cholesterol and abdominal obesity specially in men. Further studies are required to confirm the findings.