Attention Deficit Hyperactivity Disorder Medications and Sleep.
Child and adolescent psychiatric clinics of North America
July 1, 2022
Mark A Stein et al. (3 authors)
Journal ArticleReviewHuman Study
Extracted Claims (8)
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
pharmacotherapy for ADHD | increase | sleep problems | - | - | increase | #1 |
Stimulants | increase | delayed sleep onset/insomnia | - | - | associated with | #2 |
nonstimulants | increase | daytime sleepiness | - | - | associated with | #3 |
- | decrease | most effects | - | - | improve over time | #4 |
pharmacotherapy for ADHD | increase | sleep | preschoolers and adolescents | - | adverse effects on sleep | #5 |
behavioral therapy | increase | sleep | - | - | interventions to improve | #6 |
changing dose schedules or formulations | increase | sleep | - | - | interventions to improve | #7 |
melatonin | increase | sleep | - | - | adding a sleep-promoting agent | #8 |
Abstract
Sleep problems are common and often increase when initiating pharmacotherapy for ADHD. Stimulants are commonly associated with delayed sleep onset/insomnia although nonstimulants can be associated with daytime sleepiness. There is a wide variability in severity and duration of sleep effects, but most effects are mild and improve over time. Although sleep problems occur in all age groups, preschoolers and adolescents appear to be more vulnerable to adverse effects on sleep than adults and children. Interventions to improve sleep include behavioral therapy, changing dose schedules or formulations, and adding a sleep-promoting agent such as melatonin.
Medical Subject Headings (MeSH)
AdolescentAdultAttention Deficit Disorder with HyperactivityCentral Nervous System StimulantsChildHumansSleepSleep Initiation and Maintenance DisordersSleep Wake Disorders
Study Links
PubMed ID35697398
Citation Metrics
Total Citations5
Citations/Year1.7
Relative Citation Ratio1.04
NIH Percentile51.6%
Research Impact Scores
APT Score0.50
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