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The Feasibility of a Mindfulness Intervention for Depression in People with Mild Dementia: A Pilot Randomized Controlled Trial.

Clinical gerontologist
January 1, 2023
Deirdre Noone et al. (8 authors)
Randomized Controlled TrialJournal ArticleResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to assess the feasibility of an adapted MBCT intervention for people with mild dementia and depression and explore its potential benefits compared to treatment as usual (TAU).

Results Summary

The MBCT intervention was feasible in terms of attendance and attrition but did not show significant improvements in depression, anxiety, quality of life, or cognition compared to TAU. Recruitment within the timeframe was also deemed unfeasible.

Population

People with mild dementia and depression recruited from memory services.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
adapted Mindfulness Based Cognitive Therapy (MBCT) intervention
no change
feasibility
people with mild dementia and depression
high attendance and low levels of attrition
was feasible
#1
recruitment
no change
recruitment
people with dementia and depression
not enough participants within the recruitment time-frame
was not feasible
#2
adapted Mindfulness Based Cognitive Therapy (MBCT) intervention
no change
depression
people with dementia and depression
no significant change
did not show significant improvements
#3
adapted Mindfulness Based Cognitive Therapy (MBCT) intervention
no change
anxiety
people with dementia and depression
no significant change
did not show significant improvements
#4
adapted Mindfulness Based Cognitive Therapy (MBCT) intervention
no change
quality of life (QOL)
people with dementia and depression
no significant change
did not show significant improvements
#5
adapted Mindfulness Based Cognitive Therapy (MBCT) intervention
no change
cognition
people with dementia and depression
no significant change
did not show significant improvements
#6
Abstract

OBJECTIVES: This preliminary study aimed to establish the feasibility of running an adapted Mindfulness Based Cognitive Therapy (MBCT) intervention for people with mild dementia and depression. It also aimed to conduct an exploratory analysis as to whether the MBCT intervention would lead to greater improvements in measures of depression, anxiety, quality of life and cognition, as compared to treatment as usual (TAU). METHODS: A single-blind, multisite, feasibility randomized controlled trial was used. People with dementia and depression were recruited from participating memory services. Twenty participants were randomized to either an adapted MBCT and TAU group (n = 10) or TAU (n = 10). Measures of depression, anxiety, quality of life (QOL), and cognition were assessed at baseline and follow-up. RESULTS: The intervention was feasible in terms of high attendance and low levels of attrition. It was not judged feasible to recruit enough participants within the recruitment time-frame. The MBCT group did not show significant improvements in depression, anxiety, QOL, and cognition at follow-up, as compared to TAU. CONCLUSION: There is currently inadequate evidence to recommend this adapted MBCT intervention for people with dementia for the treatment of depression within memory services. The MBCT intervention needs redevelopment and piloting before further testing in an RCT.

Medical Subject Headings (MeSH)
HumansMindfulnessDepressionQuality of LifeFeasibility StudiesPilot ProjectsSingle-Blind MethodDementia
Study Links
Quality Scores
SafetyNot Assessed
Efficacy30/10
Quality65/10
Citation Metrics
Total Citations3
Citations/Year1.5
Relative Citation Ratio0.83
NIH Percentile43.4%
Research Impact Scores
APT Score0.25
Weight Score2.29
Normalized Score0.45
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