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Expectations affect pain sensitivity changes during massage.

The Journal of manual & manipulative therapy
April 1, 2023
Abigail T Wilson et al. (7 authors)
Randomized Controlled TrialJournal ArticleResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to examine how positive and negative expectations influence pain sensitivity changes during pain-free and pain-inducing massage.

Results Summary

The study found that positive expectations significantly increased pressure pain thresholds during pain-inducing massage compared to negative expectations, particularly at minutes 3 and 4. Expectations were shown to impact pain sensitivity changes during massage.

Population

56 healthy participants

Effective Dosage

Not specified

Duration

Minutes 3 and 4 of massage (exact total duration not specified)

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
positive expectation instructional set
increase
Pressure pain threshold (PPT)
healthy participants
-
demonstrated significantly higher
#1
negative expectation instructional set
decrease
Pressure pain threshold (PPT)
healthy participants
-
demonstrated significantly lower
#2
pain-inducing massage
neutral
pain sensitivity
-
-
produces changes in
#3
cold pressor task
neutral
pain sensitivity
-
-
produces comparable changes in
#4
Abstract

BACKGROUND: Pain-inducing massage produces comparable changes in pain sensitivity as a cold pressor task, suggesting shared neurophysiological mechanisms of conditioned pain modulation. Manual therapy and conditioned pain modulation are influenced by positive and negative expectations. Therefore, the purpose of this study was to examine the effects of positive and negative expectations on pain-free and pain-inducing massage. METHODS: 56 healthy participants were randomly assigned to receive a positive or negative expectation instructional set followed by a pain-inducing or a pain-free massage. Pressure pain threshold (PPT) was measured followed by each interval of massage. A repeated measures ANCOVA controlling for post-randomization differences in sex tested for massage x expectation set x PPT interaction effects, as well as two-way interaction effects. RESULTS: A significant three-way interaction effect (p = 0.04) and time x expectation interaction effect was observed for individuals receiving pain inducing massage (p = 0.02). Individuals who received the positive expectation instructional set demonstrated significantly higher PPT at minutes 3 and 4 of massage compared to individuals who received the negative expectation instructional set. CONCLUSIONS: Expectations impact pain sensitivity changes produced during massage. Clinicians planning to provide pain-inducing massage should consider the role of expectations in modulating pain sensitivity changes.

Medical Subject Headings (MeSH)
HumansPain ThresholdMotivationPainPain MeasurementMassage
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations4
Citations/Year2.0
Relative Citation Ratio1.90
NIH Percentile73%
Research Impact Scores
APT Score0.50
Weight Score2.74
Normalized Score0.67
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