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Psychotherapeutic treatments for generalized anxiety disorder: cognitive and behavioral therapies, enhancement strategies, and emerging efforts.

Expert review of neurotherapeutics
September 1, 2022
Michelle G Newman et al. (6 authors)
ReviewJournal ArticleResearch Support, N.I.H., ExtramuralHuman Study
Study Details

Study Goal

The researchers aimed to examine the efficacy of mindfulness-based CBT as an enhancement to traditional CBT for generalized anxiety disorder (GAD).

Results Summary

The abstract suggests that mindfulness-based CBT shows promise in improving upon traditional CBT for GAD, though more research is needed to determine its effectiveness for specific individuals and mechanisms of change.

Population

Individuals with generalized anxiety disorder (GAD).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (9)
InterventionDirectionEndpointPopulationDosageImpactClaim #
cognitive behavioral therapy (CBT)
decrease
generalized anxiety disorder (GAD)
-
-
is efficacious
#1
interpersonal and emotional processing therapy
decrease
generalized anxiety disorder (GAD)
-
-
have shown some promise in improving upon CBT
#2
mindfulness-based CBT
decrease
generalized anxiety disorder (GAD)
-
-
have shown some promise in improving upon CBT
#3
emotion regulation therapy
decrease
generalized anxiety disorder (GAD)
-
-
have shown some promise in improving upon CBT
#4
intolerance of uncertainty therapy
decrease
generalized anxiety disorder (GAD)
-
-
have shown some promise in improving upon CBT
#5
the unified protocol
decrease
generalized anxiety disorder (GAD)
-
-
have shown some promise in improving upon CBT
#6
metacognitive therapy
decrease
generalized anxiety disorder (GAD)
-
-
have shown some promise in improving upon CBT
#7
motivational interviewing
decrease
generalized anxiety disorder (GAD)
-
-
have shown some promise in improving upon CBT
#8
contrast avoidance targeted treatment
decrease
generalized anxiety disorder (GAD)
-
-
have shown some promise in improving upon CBT
#9
Abstract

INTRODUCTION: Generalized anxiety disorder (GAD) is common and disabling. Different versions of cognitive behavioral therapy (CBT) have been tested, but no treatment works for everyone. Therefore, researchers have attempted approaches to enhance CBT. AREAS COVERED: The current narrative review examines meta-analyses and individual trials of CBT-based treatments for GAD. We focus on CBT and its cognitive and behavioral components as well as efforts to enhance CBT and its dissemination and generalizability. Enhancement efforts included interpersonal and emotional processing therapy, mindfulness-based CBT, emotion regulation therapy, intolerance of uncertainty therapy, the unified protocol, metacognitive therapy, motivational interviewing, and contrast avoidance targeted treatment. Emerging strategies to enhance dissemination have focused on technologically based treatments. Attempts at generalizability have included examination of efficacy within diverse racial and ethnic groups. EXPERT OPINION: We conclude that CBT is efficacious, and a number of enhancement efforts have shown some promise in improving upon CBT in single trials. However, more research is needed, particularly efforts to determine which enhancements work best for which individuals and what are the mechanisms of change. Furthermore, few technological interventions have been compared to active treatments. Finally, much more attention needs to be paid to ethnic and racial diversity in randomized controlled trials.

Medical Subject Headings (MeSH)
HumansAnxiety DisordersCognitive Behavioral TherapyBehavior TherapyMotivational InterviewingPsychotropic DrugsCognitionTreatment Outcome
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality80/10
Citation Metrics
Total Citations10
Citations/Year3.3
Relative Citation Ratio1.66
NIH Percentile68.5%
Research Impact Scores
APT Score0.75
Weight Score2.64
Normalized Score0.64
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