Melatonin for sleep disorders in people with autism: Systematic review and meta-analysis.
Progress in neuro-psychopharmacology & biological psychiatry
January 1, 1970
Hellen Araujo Nogueira et al. (4 authors)
Meta-AnalysisSystematic ReviewJournal ArticleReviewHuman Study
Extracted Claims (2)
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Melatonin | increase | sleep quality | people with autistic spectrum disorder (ASD) | - | is a potential therapeutic intervention for improving | #1 |
melatonin | increase | total sleep time | people with ASD | standardized mean difference- SMD = 0.78; 95%CI = 0.35; 1.21 | presented a positive effect on | #2 |
Abstract
Melatonin is a potential therapeutic intervention for improving sleep quality in people with autistic spectrum disorder (ASD). We investigate the effect of using melatonin as a sleep disorder treatment in people with ASD. Interventionist studies were searched in seven databases. A total of 595 references were identified, 15 of which were eligible for the systemic review and meta-analysis. Melatonin use presented a positive effect on total sleep time (standardized mean difference- SMD = 0.78; 95%CI = 0.35; 1.21; I
Medical Subject Headings (MeSH)
HumansMelatoninAutistic DisorderSleepPolysomnographyAutism Spectrum DisorderSleep Wake Disorders
Study Links
PubMed ID36584862
Citation Metrics
Total Citations20
Citations/Year10.0
Relative Citation Ratio6.17
NIH Percentile95.1%
Research Impact Scores
APT Score0.95
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