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The management of sleep disturbances in children with attention-deficit/hyperactivity disorder (ADHD): an update of the literature.

Expert review of neurotherapeutics
June 1, 2024
Samuele Cortese et al. (16 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the current state of RCTs on interventions for sleep disorders in individuals with ADHD, including potential alternative interventions like light therapy.

Results Summary

The abstract does not provide specific results on light therapy, only mentioning it as an area needing further research in future RCTs.

Population

Individuals with ADHD and comorbid sleep disorders.

Effective Dosage

Not available

Duration

Not available

Interactions

None mentioned

Extracted Claims (2)
InterventionDirectionEndpointPopulationDosageImpactClaim #
behavioral intervention
decrease
sleep disorders associated with ADHD
individuals with ADHD
-
supporting
#1
melatonin
decrease
sleep disorders associated with ADHD
individuals with ADHD
-
supporting
#2
Abstract

INTRODUCTION: Sleep disorders represent an important comorbidity in individuals with ADHD. While the links between ADHD and sleep disturbances have been extensively investigated, research on the management of sleep disorders in individuals with ADHD is relatively limited, albeit expanding. AREAS COVERED: The authors searched PubMed, Medline, PsycInfo, Embase+Embase Classic, Web of Sciences databases, and clinicaltrials.gov up to 4 January 2024, for randomized controlled trials (RCTs) of any intervention for sleep disorders associated with ADHD. They retained 16 RCTs (eight on pharmacological and eight on non-pharmacological interventions), supporting behavioral intervention and melatonin, and nine ongoing RCTs registered on clinicaltrials.gov. EXPERT OPINION: The pool of RCTs testing interventions for sleep disorders in individuals with ADHD is expanding. However, to inform clinical guidelines, there is a need for additional research in several areas, including 1) RCTs based on a precise phenotyping of sleep disorders; 2) pragmatic RCTs recruiting neurodevelopmental populations representative of those seen in clinical services; 3) trials testing alternative interventions (e.g. suvorexant or light therapy) or ways to deliver them (e.g. online); 4) sequential and longer-term RCTs; 5) studies testing the impact of sleep interventions on outcomes other than sleep; 6) and implementation of advanced evidence synthesis and precision medicine approaches.

Medical Subject Headings (MeSH)
HumansAttention Deficit Disorder with HyperactivityChildSleep Wake DisordersRandomized Controlled Trials as TopicMelatoninBehavior Therapy
Study Links
Quality Scores
SafetyNot Assessed
Quality75/10
Citation Metrics
Total Citations5
Citations/Year5.0
Relative Citation Ratio2.32
Research Impact Scores
APT Score0.75
Weight Score2.76
Normalized Score0.55
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