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Relationship between vitamin D deficiency and gestational diabetes: a narrative review.

Frontiers in endocrinology
January 1, 2024
Caiqiong Lin et al. (2 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to review the relationship between vitamin D deficiency and gestational diabetes mellitus (GDM), including its mechanisms, genetic factors, and the impact of supplementation.

Results Summary

The study highlights that vitamin D deficiency is prevalent among pregnant and pre-pregnancy women and increases GDM risk. It also explores vitamin D's role in glucose metabolism and the potential benefits of supplementation.

Population

Pregnant and pre-pregnancy women

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Vitamin D
neutral
bone health
-
-
plays a critical role
#1
Vitamin D
increase
insulin sensitivity
-
-
has been shown to improve
#2
Vitamin D
increase
glucose tolerance
-
-
has been shown to improve
#3
Vitamin D deficiency
increase
gestational diabetes mellitus (GDM)
pregnant and pre-pregnancy women
-
increases the risk of developing
#4
Abstract

Vitamin D, often referred to as the "sunshine vitamin," is an essential fat-soluble vitamin that plays a critical role in bone health and has been shown to improve insulin sensitivity and glucose tolerance. Vitamin D deficiency is prevalent among pregnant and pre-pregnancy women, which increases the risk of developing gestational diabetes mellitus (GDM), a common complication during pregnancy. Recent studies have explored various aspects of the relationship between vitamin D deficiency and GDM, including the mechanisms by which vitamin D affects glucose metabolism, the role of the vitamin D receptor gene, and the impact of routine vitamin D supplementation before and during pregnancy. This paper will review the current research progress in these areas.

Medical Subject Headings (MeSH)
HumansDiabetes, GestationalPregnancyVitamin D DeficiencyFemaleVitamin DDietary SupplementsInsulin ResistanceReceptors, Calcitriol
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Citation Metrics
Total Citations1
Citations/Year1.0
Research Impact Scores
APT Score0.25
Weight Score2.60
Normalized Score0.66
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