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Enhancing recovery in non-small cell lung cancer patients through mindfulness training and Jinshui Liujun decoction supplementation.

World journal of psychiatry
March 19, 2025
Haewon Byeon
Journal ArticleHuman StudyMolecular Study
Study Details

Study Goal

The researchers aimed to determine whether combining mindfulness-based stress reduction training (MSRT) and flavored Jinshui Liujun decoction (FJLD) with conventional chemotherapy improves immune function and emotional well-being in non-small cell lung cancer patients.

Results Summary

The study found significant improvements in progression-free survival, Karnofsky performance status scores, immune function markers, and reductions in negative emotions (anxiety and depression) in patients receiving MSRT + FJLD alongside conventional chemotherapy compared to chemotherapy alone.

Population

Non-small cell lung cancer patients

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
mindfulness-based stress reduction training (MSRT) + flavored Jinshui Liujun decoction (FJLD) + conventional chemotherapy (CC)
increase
median progression-free survival
non-small cell lung cancer patients
20.50 months in TG vs 13.10 months in CG
significant improvements in
#1
mindfulness-based stress reduction training (MSRT) + flavored Jinshui Liujun decoction (FJLD) + conventional chemotherapy (CC)
increase
Karnofsky performance status scores
non-small cell lung cancer patients
60 in TG vs 50 in CG
significant improvements in
#2
mindfulness-based stress reduction training (MSRT) + flavored Jinshui Liujun decoction (FJLD) + conventional chemotherapy (CC)
increase
immune cell ratios
non-small cell lung cancer patients
-
significant improvements in
#3
mindfulness-based stress reduction training (MSRT) + flavored Jinshui Liujun decoction (FJLD) + conventional chemotherapy (CC)
decrease
self-rating anxiety scale scores
non-small cell lung cancer patients
significantly lower in TG
reductions in
#4
mindfulness-based stress reduction training (MSRT) + flavored Jinshui Liujun decoction (FJLD) + conventional chemotherapy (CC)
decrease
self-rating depression scale scores
non-small cell lung cancer patients
significantly lower in TG
reductions in
#5
Abstract

This article delves into the research conducted by Liu DW et al on the integration of mindfulness-based stress reduction training (MSRT) and flavored Jinshui Liujun decoction (FJLD) with conventional chemotherapy (CC) in the treatment of non-small cell lung cancer. The study investigates the impact of this combined approach on immune function and emotional well-being of non-small cell lung cancer patients. Patients were divided into a control group (CG) receiving CC alone and a treatment group (TG) receiving MSRT + FJLD alongside CC. The primary outcomes were progression-free survival and overall survival, with secondary outcomes including Karnofsky performance status scores, clinical efficacy, immune function markers, and emotional state assessments. The findings underscore significant improvements in median progression-free survival (20.50 months in TG vs 13.10 months in CG, P < 0.05), Karnofsky performance status scores (60 in TG vs 50 in CG, P < 0.05), and immune cell ratios, along with reductions in negative emotions (self-rating anxiety scale and self-rating depression scale scores significantly lower in TG, P < 0.05) among patients receiving MSRT + FJLD in conjunction with CC. This article highlights the potential of combining traditional Chinese medicine and modern psychological interventions to enhance the efficacy of conventional cancer treatments and improve patient outcomes.

Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Research Impact Scores
APT Score0.05
Weight Score1.25
Normalized Score0.69
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