Ketogenic Diet
→Body weight

1

7

1

↑ 1 (11%)

↓ 7 (78%)

— 1 (11%)

Evidence suggests Ketogenic Diet maydecreaseBody weight.

9 studies (9 claims)

Emerging evidence

Study Claims

10 of 10

Intervention	Direction	Endpoint	Type	Population	Dosage	Title
			Human	obese adults	Ketone-to-non-ketone ratios of 4:1 (KD 4:1) and 1.7:1 (KD 1.7:1)	Two-Week Exclusive Supplementation of Modified Ketogenic Nutrition Drink Reserves Lean Body Mass and Improves Blood Lipid Profile in Obese Adults: A Randomized Clinical Trial.
			Animal	Sprague-Dawley (SD) rats	Different fat-to-carbohydrate ratios under the same apparent metabolizable energy level (specific amounts not provided)	Generalized Ketogenic Diet Induced Liver Impairment and Reduced Probiotics Abundance of Gut Microbiota in Rat.
			Human	overweight or obese polycystic ovary syndrome (PCOS) patients	Not specified.	Impact of short-term ketogenic diet on sex hormones and glucose-lipid metabolism in overweight or obese patients with polycystic ovary syndrome.
			Human	overweight or obese polycystic ovary syndrome (PCOS) patients	Not specified.	Impact of short-term ketogenic diet on sex hormones and glucose-lipid metabolism in overweight or obese patients with polycystic ovary syndrome.
			Animal	obesity and diabetes	Not specified	Gut Microbiota Modulates Fgf21 Expression and Metabolic Phenotypes Induced by Ketogenic Diet.
			Human	participants with obesity	Carbohydrate intake ranged from 7-27% of daily energy	Ketogenic Diet Intervention for Obesity Weight-Loss- A Narrative Review, Challenges, and Open Questions.
			Human	34 male overweight subjects; aged between 25 and 65 years who were overall healthy apart from overweight	Not specified	Effects of n-3 polyunsaturated fatty acids (ω-3) supplementation on some cardiovascular risk factors with a ketogenic Mediterranean diet.
			Animal	KC mice	KD (%kcal: 84% fat, 15% protein, 1% carbohydrate).	The Impact of a Ketogenic Diet on Late-Stage Pancreatic Carcinogenesis in Mice: Efficacy and Safety Studies.
			AnimalMolecular	letrozole-induced PCOS mouse model mice	KD with 89.9% (kcal) fat.	A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice.
			Human	37-year-old obese woman with longstanding OCD and ulcerative colitis	Personalized whole-food ketogenic diet (KMT 1:5:1 ratio).	Remission of OCD and ulcerative colitis with a ketogenic diet: Case Report.